Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 12/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27150451 | 1.00 | USP7 (0.59) | USP7KCNH2CHRNB2CHRNA4ROCK1 | |
| SCHEMBL27118488 | 1.00 | USP7 (0.59) | USP7KCNH2CHRNB2CHRNA4ROCK1 | |
| Hydrochloric Acid SCHEMBL27142510 | 0.99 | USP7 (0.58) | USP7KCNH2CHRNB2CHRNA4ROCK1 | |
| Hydrochloric Acid SCHEMBL27142511 | 0.99 | USP7 (0.58) | USP7KCNH2CHRNB2CHRNA4ROCK1 | |
| Hydrochloric Acid SCHEMBL30781319 | 0.99 | USP7 (0.58) | USP7KCNH2CHRNB2CHRNA4ROCK1 | |
| SCHEMBL30781111 | 0.92 | USP7 (0.56) | USP7KCNH2USP2ALDH1A1TP53 | |
| SCHEMBL27118494 | 0.92 | USP7 (0.56) | USP7KCNH2USP2ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL30781249 | 0.91 | USP7 (0.55) | USP7KCNH2USP2ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL27137229 | 0.91 | USP7 (0.55) | USP7KCNH2USP2ALDH1A1TP53 | |
| SCHEMBL30781187 | 0.89 | USP7 (0.48) | USP7KCNH2USP2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024042494-A1 | SUBSTITUTED PYRROLOTRIAZINES | MOLECURE SA (PL) | 2024-02-29 | — | — | WO | claimed |
| WO-2024042494-A1 | SUBSTITUTED PYRROLOTRIAZINES | MOLECURE SA (PL) | 2024-02-29 | — | — | WO | disclosed |