Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29741837 | 0.76 | — | — | |
| SCHEMBL1911881 | 0.76 | — | — | |
| SCHEMBL10187337 | 0.74 | MEN1 (0.81) | SCN9ACDK5CDK1CCNB1CCNA2 | |
| SCHEMBL1097149 | 0.73 | MEN1 (0.78) | SCN9ACDK5CDK1CCNB1CCNA2 | |
| SCHEMBL30138398 | 0.72 | CYP1A2 (0.54) | SCN9ACLK4CYP2C19 | |
| SCHEMBL20929509 | 0.72 | CYP1A2 (0.54) | SCN9ACLK4CYP2C19 | |
| SCHEMBL18469869 | 0.71 | — | — | |
| SCHEMBL374428 | 0.71 | MEN1 (0.51) | SCN9ACDK5CDK1CCNB1CCNA2 | |
| SCHEMBL19679369 | 0.71 | CDK5 (0.41) | SCN9ACDK5CDK1CCNB1CCNA2 | |
| SCHEMBL20910941 | 0.71 | CDK5 (0.41) | SCN9ACDK5CDK1CCNB1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396473-A | Imidazopyridinyl inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-12 | — | — | CN | disclosed |