Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.60 |
| ▸ | ABL1 | P00519 | 7/20 | 0.60 |
| ▸ | BCR | P11274 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.53 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | SRC | P12931 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30782442 | 0.85 | XDH (0.58) | XDHABL1BCRNPC1RAB9A | |
| SCHEMBL16363271 | 0.82 | HAVCR2 (0.68) | XDHABL1BCRNPC1RAB9A | |
| SCHEMBL30782409 | 0.82 | XDH (0.61) | XDHABL1BCRNPC1RAB9A | |
| SCHEMBL3425759 | 0.79 | ABL1 (0.82) | ABL1BCRALDH1A1MAPTLMNA | |
| SCHEMBL30782431 | 0.77 | ABL1 (0.55) | XDHABL1BCRHAVCR2 | |
| SCHEMBL16363253 | 0.77 | ABL1 (0.69) | XDHABL1BCRNPC1RAB9A | |
| SCHEMBL16363279 | 0.77 | HAVCR2 (0.68) | XDHABL1BCRNPC1RAB9A | |
| SCHEMBL16363248 | 0.75 | HAVCR2 (0.61) | XDHABL1BCRNPC1RAB9A | |
| SCHEMBL16363247 | 0.75 | HAVCR2 (0.69) | XDHABL1BCRNPC1RAB9A | |
| SCHEMBL3399964 | 0.74 | ABL1 (1.00) | ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561260-A | Heterocyclic compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-02-13 | — | — | CN | disclosed |