Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 13/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.34 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 3/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30782873 | 1.00 | KDM4C (0.38) | KDM4CNOTUMPARP15PARP14PARP10 | |
| SCHEMBL30782834 | 1.00 | KDM4C (0.38) | KDM4CNOTUMPARP15PARP14PARP10 | |
| SCHEMBL30782851 | 0.86 | NOTUM (0.38) | KDM4CNOTUMPARP15PARP14PARP10 | |
| SCHEMBL30782907 | 0.86 | NOTUM (0.38) | KDM4CNOTUMPARP15PARP14PARP10 | |
| SCHEMBL27231290 | 0.86 | KDM4C (0.42) | KDM4CKDM6BP2RX7 | |
| SCHEMBL27214634 | 0.86 | KDM4C (0.42) | KDM4CKDM6BP2RX7 | |
| Hydrochloric Acid SCHEMBL27214593 | 0.85 | LOXL2 (0.38) | KDM4CNOTUMPARP15PARP14PARP10 | |
| Hydrochloric Acid SCHEMBL29923508 | 0.85 | LOXL2 (0.38) | KDM4CNOTUMPARP15PARP14PARP10 | |
| SCHEMBL27214580 | 0.85 | KDM4C (0.37) | KDM4CHTR1AKDM6BP2RX7 | |
| SCHEMBL27230891 | 0.85 | KDM4C (0.37) | KDM4CHTR1AKDM6BP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4593954-A1 | COMPOUNDS FOR THE TREATMENT OF A CENTRAL NERVOUS SYSTEM DISEASE OR DISORDER | PGI Drug Discovery LLC (US) | 2025-08-06 | — | — | EP | disclosed |
| WO-2024073383-A1 | COMPOUNDS FOR THE TREATMENT OF A CENTRAL NERVOUS SYSTEM DISEASE OR DISORDER | PGI DRUG DISCOVERY LLC (US) | 2024-04-04 | — | — | WO | disclosed |