Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.32 |
| ▸ | WNT3A | P56704 | 4/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | BUB1 | O43683 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
| ▸ | SPR | P35270 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30782903 | 1.00 | BRD4 (0.34) | BRD4CREBBPUCHL1AAK1WNT3A | |
| SCHEMBL30782909 | 0.90 | GRM5 (0.34) | UCHL1AAK1 | |
| SCHEMBL30782862 | 0.90 | GRM5 (0.34) | UCHL1AAK1 | |
| SCHEMBL30782883 | 0.89 | PARP15 (0.35) | UCHL1PDK2HTR2CSLC6A4 | |
| SCHEMBL30782833 | 0.89 | PARP15 (0.35) | UCHL1PDK2HTR2CSLC6A4 | |
| SCHEMBL30782900 | 0.83 | ACACB (0.41) | BRD4CREBBPUCHL1AAK1WNT3A | |
| SCHEMBL31664593 | 0.82 | BRD4 (0.36) | BRD4CREBBPPDK2HTR2CSLC6A4 | |
| SCHEMBL31664591 | 0.82 | BRD4 (0.36) | BRD4CREBBPPDK2HTR2CSLC6A4 | |
| SCHEMBL29923610 | 0.81 | BRD4 (0.33) | BRD4CREBBPUCHL1AAK1WNT3A | |
| SCHEMBL29923128 | 0.81 | BRD4 (0.33) | BRD4CREBBPUCHL1AAK1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4593954-A1 | COMPOUNDS FOR THE TREATMENT OF A CENTRAL NERVOUS SYSTEM DISEASE OR DISORDER | PGI Drug Discovery LLC (US) | 2025-08-06 | — | — | EP | disclosed |
| WO-2024073383-A1 | COMPOUNDS FOR THE TREATMENT OF A CENTRAL NERVOUS SYSTEM DISEASE OR DISORDER | PGI DRUG DISCOVERY LLC (US) | 2024-04-04 | — | — | WO | disclosed |