Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.35 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 6/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 4/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30782883 | 1.00 | PARP15 (0.35) | PARP15PARP14PARP10TIPARPPARP16 | |
| SCHEMBL30782852 | 0.89 | BRD4 (0.34) | UCHL1PDK2HTR2CSLC6A4 | |
| SCHEMBL30782903 | 0.89 | BRD4 (0.34) | UCHL1PDK2HTR2CSLC6A4 | |
| SCHEMBL30782909 | 0.87 | GRM5 (0.34) | UCHL1 | |
| SCHEMBL30782862 | 0.87 | GRM5 (0.34) | UCHL1 | |
| SCHEMBL30782921 | 0.87 | UCHL1 (0.34) | PARP15PARP14PARP10TIPARPPARP16 | |
| SCHEMBL30782914 | 0.87 | UCHL1 (0.34) | PARP15PARP14PARP10TIPARPPARP16 | |
| SCHEMBL30782865 | 0.86 | UCHL1 (0.38) | PARP15PARP14PARP10TIPARPPARP16 | |
| SCHEMBL30782882 | 0.84 | ACACB (0.39) | PARP15PARP14PARP10TIPARPPARP16 | |
| SCHEMBL29923280 | 0.82 | KDM4C (0.33) | PARP15PARP14PARP10TIPARPPARP16 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4593954-A1 | COMPOUNDS FOR THE TREATMENT OF A CENTRAL NERVOUS SYSTEM DISEASE OR DISORDER | PGI Drug Discovery LLC (US) | 2025-08-06 | — | — | EP | disclosed |
| WO-2024073383-A1 | COMPOUNDS FOR THE TREATMENT OF A CENTRAL NERVOUS SYSTEM DISEASE OR DISORDER | PGI DRUG DISCOVERY LLC (US) | 2024-04-04 | — | — | WO | disclosed |