Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 4/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 5/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 4/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25659973 | 0.79 | ADRA2A (0.50) | ADRA2AADRA2BADRA1AADRA2CHTR2B | |
| SCHEMBL25166562 | 0.79 | ADRA2A (0.50) | ADRA2AADRA2BADRA1AADRA2CHTR2B | |
| SCHEMBL4753561 | 0.79 | ADRA2A (0.50) | ADRA2AADRA2BADRA1AADRA2CHTR2B | |
| SCHEMBL23976381 | 0.79 | ADRA2A (0.50) | ADRA2AADRA2BADRA1AADRA2CHTR2B | |
| SCHEMBL29923638 | 0.75 | ADRA2A (0.47) | ADRA2AADRA2BADRA1AADRA2CHTR2B | |
| SCHEMBL27214559 | 0.75 | ADRA2A (0.47) | ADRA2AADRA2BADRA1AADRA2CHTR2B | |
| SCHEMBL2729067 | 0.75 | ADRA2A (0.47) | ADRA2AADRA2BADRA1AADRA2CHTR2B | |
| SCHEMBL2729875 | 0.75 | ADRA2A (0.47) | ADRA2AADRA2BADRA1AADRA2CHTR2B | |
| SCHEMBL31347606 | 0.74 | ADRA2A (0.40) | ADRA2AADRA2BADRA1AADRA2C | |
| Hydrochloric Acid SCHEMBL30782876 | 0.73 | ADRA2A (0.46) | ADRA2AADRA2BADRA1AADRA2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4593954-A1 | COMPOUNDS FOR THE TREATMENT OF A CENTRAL NERVOUS SYSTEM DISEASE OR DISORDER | PGI Drug Discovery LLC (US) | 2025-08-06 | — | — | EP | disclosed |
| WO-2024073383-A1 | COMPOUNDS FOR THE TREATMENT OF A CENTRAL NERVOUS SYSTEM DISEASE OR DISORDER | PGI DRUG DISCOVERY LLC (US) | 2024-04-04 | — | — | WO | disclosed |