Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.42 |
| ▸ | GRM5 | P41594 | 4/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | DTYMK | P23919 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21748845 | 1.00 | POLB (0.43) | POLBGPR119GRM5GRM1PDE10A | |
| SCHEMBL21748843 | 1.00 | POLB (0.43) | POLBGPR119GRM5GRM1PDE10A | |
| SCHEMBL21748717 | 0.86 | POLB (0.45) | POLBGPR119GRM5GRM1USP30 | |
| SCHEMBL21773364 | 0.79 | USP30 (0.46) | GPR119USP30MAPK1 | |
| SCHEMBL4481228 | 0.79 | USP30 (0.46) | GPR119USP30MAPK1 | |
| SCHEMBL4481232 | 0.79 | USP30 (0.46) | GPR119USP30MAPK1 | |
| SCHEMBL30783224 | 0.77 | JAK2 (0.52) | POLBGPR119 | |
| SCHEMBL21775442 | 0.76 | GPR119 (0.50) | POLBGPR119USP30GCK | |
| SCHEMBL30783205 | 0.76 | GPR119 (0.50) | POLBGPR119USP30GCK | |
| SCHEMBL21748693 | 0.76 | GPR119 (0.50) | POLBGPR119USP30GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236423-B | Piperidinyl-3- (aryloxy) propanamides and propionic acid esters | 武田药品工业株式会社 | 2024-02-06 | — | — | CN | disclosed |