Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | GLP1R | P43220 | 8/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRND | Q07001 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.35 |
| ▸ | NMT2 | O60551 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30783455 | 0.90 | FOLH1 (0.37) | FOLH1OPRK1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL30783476 | 0.87 | ALB (0.44) | ALBCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL30783466 | 0.87 | ALB (0.54) | ALBFOLH1GLP1R | |
| SCHEMBL31298666 | 0.85 | CA1 (0.44) | ALBCA1CA2CALCRL | |
| SCHEMBL27262184 | 0.84 | CD40 (0.45) | ALBOPRK1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL30783460 | 0.82 | CPB1 (0.52) | CALCRL | |
| SCHEMBL30783503 | 0.81 | KLK7 (0.41) | FOLH1 | |
| SCHEMBL27262252 | 0.81 | CA1 (0.43) | ALBGLP1RCA1CA2 | |
| SCHEMBL27262327 | 0.81 | CALCRL (0.42) | OPRK1GLP1RCHRNA1CHRNGCHRNB1 | |
| SCHEMBL30783519 | 0.80 | SIRT2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4561998-A1 | FIBROBLAST ACTIVATION PROTEIN-TARGETED COMPOSITIONS AND METHODS OF USE THEREOF | Ratio Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2025029608-A1 | FIBROBLAST ACTIVATION PROTEIN-TARGETED COMPOSITIONS AND METHODS OF USE THEREOF | RATIO THERAPEUTICS, INC. (US) | 2025-02-06 | — | — | WO | disclosed |
| WO-2024026072-A1 | FIBROBLAST ACTIVATION PROTEIN-TARGETED COMPOSITIONS AND METHODS OF USE THEREOF | RATIO THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |