Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 16/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.37 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30783939 | 0.96 | PIK3CB (0.40) | PIK3CBAKT1AKT2AKT3POLB | |
| SCHEMBL30783599 | 0.89 | PIK3CB (0.37) | PIK3CBAKT1AKT2AKT3POLB | |
| SCHEMBL30784386 | 0.88 | DPP4 (0.37) | PIK3CBPOLBMAPK1DPP4GAA | |
| SCHEMBL30784369 | 0.88 | PIK3CB (0.38) | PIK3CBAKT1AKT2AKT3 | |
| SCHEMBL30783773 | 0.87 | CYP1A2 (0.44) | PIK3CBAKT1AKT2AKT3POLB | |
| SCHEMBL30784539 | 0.86 | PDE1A (0.42) | PIK3CBAKT1AKT2AKT3 | |
| SCHEMBL30783583 | 0.86 | AKT1 (0.47) | PIK3CBAKT1AKT2AKT3PIK3CD | |
| SCHEMBL30784348 | 0.86 | AKT1 (0.47) | PIK3CBAKT1AKT2AKT3PIK3CD | |
| SCHEMBL30783689 | 0.85 | PIK3CB (0.39) | PIK3CBAKT1AKT2AKT3PIK3CD | |
| SCHEMBL30784279 | 0.82 | PIM1 (0.42) | PIK3CBDPP4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026424-A1 | QUINAZOLINONE DERIVATIVES AS AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |