Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | STAT6 | P42226 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30783932 | 0.88 | PIK3CB (0.38) | DPP4POLBMAPK1GAAPIK3CB | |
| SCHEMBL30784248 | 0.88 | METAP2 (0.37) | DPP4SMN1; SMN2LMNASTAT6SOS1 | |
| SCHEMBL30784178 | 0.86 | PDE1A (0.39) | DPP4SMN1; SMN2LMNASTAT6SOS1 | |
| SCHEMBL30784172 | 0.86 | HTT (0.39) | DPP4SMN1; SMN2LMNASTAT6POLB | |
| SCHEMBL30783939 | 0.85 | PIK3CB (0.40) | DPP4POLBMAPK1PIK3CB | |
| SCHEMBL30783979 | 0.79 | PIK3CB (0.45) | S1PR1SOS1PIK3CB | |
| SCHEMBL30783599 | 0.78 | PIK3CB (0.37) | DPP4POLBALDH1A1MEN1KMT2A | |
| SCHEMBL30784369 | 0.77 | PIK3CB (0.38) | METAP2PIK3CB | |
| SCHEMBL30783773 | 0.76 | CYP1A2 (0.44) | DPP4POLBALDH1A1CYP3A4MEN1 | |
| SCHEMBL30783794 | 0.74 | HTT (0.40) | DPP4SMN1; SMN2LMNASTAT6SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026424-A1 | QUINAZOLINONE DERIVATIVES AS AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |