Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30783708 | 0.87 | HTT (0.41) | HTTDRD2DRD4DRD3CYP1A2 | |
| SCHEMBL30784241 | 0.86 | HTT (0.43) | HTTDRD2DRD4DRD3CYP1A2 | |
| SCHEMBL30784051 | 0.86 | HTT (0.43) | HTTDRD2DRD4DRD3CYP1A2 | |
| SCHEMBL30784502 | 0.85 | SMN1; SMN2 (0.43) | HTTDRD2DRD4DRD3CYP1A2 | |
| SCHEMBL30784290 | 0.85 | HTT (0.40) | HTTDRD2DRD4DRD3DPP4 | |
| SCHEMBL30784287 | 0.85 | CYP1A2 (0.43) | CYP1A2KMT2ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL25356627 | 0.84 | PTPN11 (0.39) | DRD2DRD4DRD3AKT1PTPN11 | |
| SCHEMBL30564445 | 0.84 | AKT1 (0.44) | DRD2DRD4DRD3ALDH1A1AKT1 | |
| SCHEMBL30784281 | 0.84 | DPP4 (0.45) | HTTDRD2DRD4DRD3CYP1A2 | |
| SCHEMBL30783853 | 0.84 | HTT (0.39) | HTTDRD2DRD4DRD3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026424-A1 | QUINAZOLINONE DERIVATIVES AS AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |