Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | PRKDC | P78527 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30784051 | 0.85 | HTT (0.43) | DPP4HTTDRD2DRD4DRD3 | |
| SCHEMBL30784241 | 0.85 | HTT (0.43) | DPP4HTTDRD2DRD4DRD3 | |
| SCHEMBL30784114 | 0.84 | HTT (0.42) | DPP4HTTDRD2DRD4DRD3 | |
| SCHEMBL30784502 | 0.84 | SMN1; SMN2 (0.43) | DPP4HTTDRD2DRD4DRD3 | |
| SCHEMBL30784388 | 0.84 | HTR1B (0.40) | DPP4HTTDRD2DRD4DRD3 | |
| SCHEMBL30783708 | 0.83 | HTT (0.41) | DPP4HTTDRD2DRD4DRD3 | |
| SCHEMBL30784328 | 0.83 | DPP4 (0.39) | DPP4HTTDRD2DRD4DRD3 | |
| SCHEMBL30783877 | 0.82 | HTT (0.41) | DPP4HTTDRD2DRD4DRD3 | |
| SCHEMBL30784290 | 0.81 | HTT (0.40) | DPP4HTTDRD2DRD4DRD3 | |
| SCHEMBL30784048 | 0.81 | CRHR1 (0.41) | DPP4HTTDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026424-A1 | QUINAZOLINONE DERIVATIVES AS AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |