Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 6/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.32 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30784155 | 1.00 | PBRM1 (0.33) | PBRM1DGAT2UCHL1SLC16A3SLC16A1 | |
| SCHEMBL30784439 | 0.84 | MEN1 (0.35) | UCHL1SLC16A3SLC16A1MEN1KMT2A | |
| SCHEMBL30784107 | 0.83 | KDM4E (0.39) | — | |
| SCHEMBL30783814 | 0.83 | KDM4E (0.39) | — | |
| SCHEMBL7947607 | 0.77 | RPS6KB1 (0.38) | GBA1 | |
| SCHEMBL15206013 | 0.76 | ACACB (0.39) | — | |
| SCHEMBL15205573 | 0.76 | ACACB (0.39) | — | |
| SCHEMBL4555535 | 0.75 | MAPT (0.40) | PBRM1 | |
| SCHEMBL31658773 | 0.75 | HRH4 (0.37) | — | |
| SCHEMBL31658884 | 0.75 | HRH4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026424-A1 | QUINAZOLINONE DERIVATIVES AS AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |