Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 9/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | DGKZ | Q13574 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25358167 | 0.88 | AKT1 (0.40) | PDE2AAKT1AKT2AKT3PIK3CA | |
| SCHEMBL30494860 | 0.88 | AKT1 (0.40) | PDE2AAKT1AKT2AKT3PIK3CA | |
| SCHEMBL25358173 | 0.88 | AKT1 (0.40) | PDE2AAKT1AKT2AKT3PIK3CA | |
| SCHEMBL30783794 | 0.87 | HTT (0.40) | SOS1HTTDRD2DRD4DRD3 | |
| SCHEMBL30783830 | 0.86 | HTT (0.39) | HTTDRD2DRD4DRD3KMT2A | |
| SCHEMBL30784396 | 0.86 | HTT (0.39) | HTTDRD2DRD4DRD3KMT2A | |
| SCHEMBL30783583 | 0.85 | AKT1 (0.47) | HTTDRD2DRD4DRD3KMT2A | |
| SCHEMBL30784348 | 0.85 | AKT1 (0.47) | HTTDRD2DRD4DRD3KMT2A | |
| SCHEMBL30783695 | 0.84 | HTT (0.39) | HTTDRD2DRD4DRD3KMT2A | |
| SCHEMBL30784172 | 0.84 | HTT (0.39) | HTTDRD2DRD4DRD3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026424-A1 | QUINAZOLINONE DERIVATIVES AS AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |