Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | STAT6 | P42226 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30783830 | 1.00 | HTT (0.39) | HTTCYP1A2KMT2ADRD2DRD4 | |
| SCHEMBL30783794 | 0.90 | HTT (0.40) | HTTCYP1A2KMT2ADRD2DRD4 | |
| SCHEMBL30783583 | 0.88 | AKT1 (0.47) | HTTKMT2ADRD2DRD4DRD3 | |
| SCHEMBL30784348 | 0.88 | AKT1 (0.47) | HTTKMT2ADRD2DRD4DRD3 | |
| SCHEMBL30784294 | 0.87 | PIK3CB (0.36) | CYP1A2PIK3CBAKT1SMN1; SMN2RAB9A | |
| SCHEMBL26041490 | 0.87 | AKT1 (0.42) | AKT1AKT2AKT3PTPN11KDM1A | |
| SCHEMBL30784172 | 0.87 | HTT (0.39) | HTTCYP1A2KMT2ADRD2DRD4 | |
| SCHEMBL30783695 | 0.87 | HTT (0.39) | HTTKMT2ADRD2DRD4DRD3 | |
| SCHEMBL30784462 | 0.86 | SOS1 (0.42) | HTTKMT2ADRD2DRD4DRD3 | |
| SCHEMBL30784328 | 0.85 | DPP4 (0.39) | HTTCYP1A2KMT2ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026424-A1 | QUINAZOLINONE DERIVATIVES AS AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |