⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL843718 | 0.80 | — | — | |
| SCHEMBL3073315 | 0.74 | — | — | |
| SCHEMBL611134 | 0.72 | ALDH1A1 (0.52) | — | |
| SCHEMBL1703141 | 0.70 | — | — | |
| SCHEMBL1129009 | 0.70 | ERN1 (0.33) | — | |
| SCHEMBL6959981 | 0.70 | — | — | |
| SCHEMBL129408 | 0.69 | — | — | |
| SCHEMBL1244825 | 0.68 | — | — | |
| SCHEMBL1244775 | 0.68 | — | — | |
| SCHEMBL17039811 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122059923-A | Aldehyde group-guided bi (hetero) aromatic compound and synthesis method and application thereof | 桂林理工大学 | 2026-05-19 | — | — | CN | disclosed |
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | FUJIFILM CORPORATION (JP) | 2025-10-23 | — | — | US | disclosed |
| CN-119816484-A | Novel piperazine derivative or salt thereof and pharmaceutical composition | 富士胶片株式会社 | 2025-04-11 | — | — | CN | disclosed |
| WO-2024043334-A1 | NOVEL PIPERAZINE DERIVATIVE OR SALT THEREOF AND PHARMACEUTICAL COMPOSITION | 富士フイルム株式会社 | 2024-02-29 | — | — | WO | disclosed |
| CN-115806568-A | Method for constructing heteroatom substituted xanthene derivative through palladium-catalyzed cross coupling and application | 华东师范大学 | 2023-03-17 | — | — | CN | disclosed |
| US-11517565-B2 | Bis-amines, compositions, and uses related to CXCR4 inhibition | EMORY UNIVERSITY (US) | 2022-12-06 | — | — | US | disclosed |
| CN-110194770-B | Peptidyl arginine deiminase inhibitors and uses thereof | 药捷安康(南京)科技股份有限公司 | 2022-08-09 | — | — | CN | disclosed |
| EP-3760628-A1 | PEPTIDYLARGININE DEIMINASE INHIBITOR AND USE THEREOF | Nanjing Transthera Biosciences Co., Ltd. (CN) | 2021-01-06 | — | — | EP | disclosed |
| EP-3760628-A1 | PEPTIDYLARGININE DEIMINASE INHIBITOR AND USE THEREOF | Nanjing Transthera Biosciences Co., Ltd. (CN) | 2021-01-06 | — | — | EP | disclosed |
| US-20200407370-A1 | PEPTIDYLARGININE DEIMINASE INHIBITOR AND USE THEREOF | NANJING TRANSTHERA BIOSCIENCES CO., LTD. (CN) | 2020-12-31 | — | — | US | disclosed |
| EP-1435355-A1 | Stilbeneamine derivative and electrophotosensitive material using the same | Kyocera Mita Corporation (JP) | 2004-07-07 | — | — | EP | disclosed |
| US-6653034-B2 | Stilbeneamine derivative containing thiophene ring (2-thienyl or 3-thienyl) | KYOCERA MITA CORPORATION (JP) | 2003-11-25 | — | — | US | disclosed |
| EP-0954521-B1 | 4- (THIEN-3-YL)METHYL] IMIDAZOLE DERIVATIVES HAVING ALPHA2-ADRENOCEPTOR AGONISTIC ACTIVITY | ORTHO MCNEIL PHARM INC (US) | 2003-05-14 | — | — | EP | disclosed |
| US-20020172877-A1 | Stilbeneamine derivative and electrophotosensitive material using the same | KYOCERA MITA CORPORATION (JP) | 2002-11-21 | — | — | US | disclosed |
| EP-1243588-A1 | Stilbeneamine derivative and electrophotosensitive material using the same | Kyocera Mita Corporation (JP) | 2002-09-25 | — | — | EP | disclosed |
| EP-0954521-A1 | 4- (THIEN-3-YL)METHYL] IMIDAZOLE DERIVATIVES HAVING ALPHA2-ADRENOCEPTOR AGONISTIC ACTIVITY | Ortho-McNeil Pharmaceutical, Inc. (US) | 1999-11-10 | — | — | EP | disclosed |
| US-5750720-A | ALPHA-ADRENORECEPTORS AND CENTRAL NERVOUS SYSTEMS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |
| WO-1997035858-A1 | 4-[(THIEN-3-YL)METHYL] IMIDAZOLE DERIVATIVES HAVING α2-ADRENOCEPTOR AGONISTIC ACTIVITY | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-10-02 | — | — | WO | disclosed |
| US-5120861-A | DIAZIRINE DERIVATIVES OF AROMATIC HETEROCYCLIC COMPOUNDS | SHELL RESEARCH LIMITED (GB) | 1992-06-09 | — | — | US | disclosed |
| EP-0432817-A1 | Diazirine derivatives of aromatic heterocyclic compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-06-19 | — | — | EP | disclosed |