Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1E | P28566 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27158629 | 1.00 | HTR2A (0.46) | HTR2AADRA2AADRA2BADRA2CSLC6A2 | |
| Hydrochloric Acid SCHEMBL27158280 | 0.99 | HTR2A (0.45) | HTR2AADRA2AADRA2BADRA2CSLC6A2 | |
| Hydrochloric Acid SCHEMBL27158184 | 0.80 | SLC6A2 (0.40) | SLC6A2SLC6A4HTR1ASLC6A3 | |
| Hydrochloric Acid SCHEMBL29912994 | 0.80 | SLC6A2 (0.40) | SLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL3323892 | 0.78 | SLC6A2 (0.48) | HTR2AADRA2AADRA2BADRA2CSLC6A2 | |
| SCHEMBL3325927 | 0.78 | SLC6A2 (0.48) | HTR2AADRA2AADRA2BADRA2CSLC6A2 | |
| SCHEMBL3325931 | 0.78 | SLC6A2 (0.48) | HTR2AADRA2AADRA2BADRA2CSLC6A2 | |
| SCHEMBL3327020 | 0.77 | ALOX15 (0.42) | SLC6A2SLC6A4HTR2CSLC6A3 | |
| SCHEMBL3325173 | 0.77 | ALOX15 (0.42) | SLC6A2SLC6A4HTR2CSLC6A3 | |
| SCHEMBL3327016 | 0.77 | ALOX15 (0.42) | SLC6A2SLC6A4HTR2CSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642404-A | Small molecule modulators of glucocerebrosidase activity and uses thereof | 凡况生化公司 | 2024-03-01 | — | — | CN | disclosed |