Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 8/20 | 0.37 |
| ▸ | DRD2 | P14416 | 5/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 4/20 | 0.33 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.32 |
| ▸ | BMPR1A | P36894 | 2/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.32 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.31 |
| ▸ | CNR2 | P34972 | 3/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30786099 | 0.96 | KDR (0.39) | KDRHTR2ADRD2HTR1ADRD3 | |
| SCHEMBL31475160 | 0.93 | KDR (0.40) | KDRHTR2ADRD2HTR1AKCNH2 | |
| SCHEMBL31475210 | 0.92 | DRD2 (0.37) | KDRHTR2ADRD2HTR1AHTR2C | |
| SCHEMBL30786076 | 0.92 | KDR (0.47) | KDRHTR2ADRD2HTR1ABMPR1B | |
| SCHEMBL30786078 | 0.89 | KDR (0.36) | KDRHTR2ADRD2HTR1ABMPR1B | |
| SCHEMBL31475279 | 0.89 | KDR (0.48) | KDRHTR2ADRD2DRD3BMPR1B | |
| SCHEMBL30786236 | 0.88 | KDR (0.37) | KDRHTR2ADRD2HTR1ADRD3 | |
| SCHEMBL30786061 | 0.87 | KDR (0.38) | KDRKCNH2MCHR1CNR1CNR2 | |
| SCHEMBL31475173 | 0.86 | HTR2A (0.35) | KDRHTR2ADRD2HTR1ADRD3 | |
| SCHEMBL30786075 | 0.85 | KDR (0.49) | KDRBMPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119604488-A | Protein tyrosine kinase inhibitor and medical application thereof | 苏州必扬医药科技有限公司 | 2025-03-11 | — | — | CN | disclosed |
| WO-2024032584-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | 苏州必扬医药科技有限公司 | 2024-02-15 | — | — | WO | disclosed |