Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30786186 | 1.00 | HRH3 (0.47) | HRH3KDM4EL3MBTL1HDAC8HDAC6 | |
| SCHEMBL30786193 | 0.83 | KDM4E (0.39) | HRH3KDM4EL3MBTL1 | |
| SCHEMBL30786149 | 0.81 | CHRNB2 (0.44) | HRH3KDM4EL3MBTL1HDAC6 | |
| SCHEMBL15007 | 0.79 | KDM4E (0.61) | HRH3KDM4EL3MBTL1 | |
| SCHEMBL20038511 | 0.76 | HRH3 (0.52) | HRH3HDAC8HDAC6 | |
| SCHEMBL19735731 | 0.76 | KDM4E (0.45) | KDM4EL3MBTL1 | |
| SCHEMBL7499051 | 0.74 | HRH3 (0.50) | HRH3KDM4EHDAC8HDAC6 | |
| SCHEMBL1126370 | 0.74 | HRH3 (0.50) | HRH3HDAC8HDAC6 | |
| SCHEMBL5048184 | 0.74 | HRH3 (0.50) | HRH3KDM4EL3MBTL1 | |
| SCHEMBL20038509 | 0.74 | HRH3 (0.50) | HRH3HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024032584-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | 苏州必扬医药科技有限公司 | 2024-02-15 | — | — | WO | disclosed |