Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14193258 | 0.92 | ASAH1 (0.53) | ASAH1TSHRRAB9APOLBHSD17B10 | |
| SCHEMBL5120623 | 0.87 | HSD17B10 (0.56) | ASAH1KMT2ATSHRRAB9APOLB | |
| SCHEMBL4782417 | 0.83 | ATM (0.46) | ASAH1KMT2AMEN1BCHEL3MBTL1 | |
| SCHEMBL17665507 | 0.78 | MEN1 (0.58) | ASAH1KMT2AMEN1TSHRRAB9A | |
| Hydrochloric Acid SCHEMBL31243595 | 0.78 | ASAH1 (0.45) | ASAH1KMT2AMEN1TSHRRAB9A | |
| SCHEMBL4048871 | 0.77 | ELANE (0.52) | ASAH1KMT2AMEN1TSHRRAB9A | |
| SCHEMBL6625152 | 0.77 | SLC22A12 (0.47) | ASAH1KMT2AMEN1TSHRRAB9A | |
| SCHEMBL7167380 | 0.77 | ASAH1 (0.52) | ASAH1KMT2AMEN1TSHRRAB9A | |
| SCHEMBL31707519 | 0.77 | ASAH1 (0.52) | ASAH1KMT2AMEN1TSHRRAB9A | |
| Hydrochloric Acid SCHEMBL28173345 | 0.76 | ASAH1 (0.51) | ASAH1KMT2AMEN1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024032584-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | 苏州必扬医药科技有限公司 | 2024-02-15 | — | — | WO | disclosed |