SCHEMBL6625152

SCHEMBL6625152

O=[C]COC(=O)n1ncc2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A12 Q96S37 1/20 0.47
ASAH1 Q13510 2/20 0.44
ELANE P08246 1/20 0.44
KMO O15229 1/20 0.42
POLB P06746 4/20 0.41
HSD17B10 Q99714 2/20 0.41
TSHR P16473 2/20 0.41
TFPI2 P48307 1/20 0.41
PKM P14618 1/20 0.40
CYP1A2 P05177 1/20 0.37
RECQL P46063 2/20 0.36
NPC1 O15118 4/20 0.35
RAB9A P51151 4/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
CHEK1 O14757 1/20 0.33
AURKA O14965 1/20 0.33
DAPK3 O43293 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5120623 0.83 HSD17B10 (0.56) SLC22A12ASAH1ELANEKMOPOLB
SCHEMBL31707519 0.79 ASAH1 (0.52) SLC22A12ASAH1ELANEKMOPOLB
SCHEMBL7167380 0.79 ASAH1 (0.52) SLC22A12ASAH1ELANEKMOPOLB
SCHEMBL14193258 0.79 ASAH1 (0.53) SLC22A12ASAH1ELANEKMOPOLB
Hydrochloric Acid SCHEMBL28173345 0.78 ASAH1 (0.51) SLC22A12ASAH1ELANEKMOPOLB
Hydrochloric Acid SCHEMBL31243595 0.77 ASAH1 (0.45) SLC22A12ASAH1ELANEKMOPOLB
SCHEMBL30786241 0.77 ASAH1 (0.57) SLC22A12ASAH1ELANEKMOPOLB
SCHEMBL27780009 0.76 SLC22A12 (0.52) SLC22A12ASAH1ELANEKMOPOLB
SCHEMBL4048871 0.76 ELANE (0.52) SLC22A12ASAH1ELANEKMOPOLB
SCHEMBL4303719 0.74 KMT2A (0.46) SLC22A12ASAH1ELANEHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1289984-A4 NOVEL OXAZOLIDINONE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF DONG A PHARM CO LTD (KR) 2004-11-24 EP claimed
EP-1289984-A1 NOVEL OXAZOLIDINONE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF Dong A Pharmaceutical Co. Ltd. (KR) 2003-03-12 EP claimed
WO-2001094342-A1 NOVEL OXAZOLIDINONE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF DONG A PHARM. CO., LTD. (KR) 2001-12-13 WO claimed