SCHEMBL30786258

SCHEMBL30786258

C=Cc1ccc(CCOS(=O)(=O)c2ccc(C)cc2)cn1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.37
CA9 Q16790 3/20 0.37
CA12 O43570 2/20 0.37
CA2 P00918 4/20 0.36
CNR2 P34972 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PSMD10 O75832 1/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
STAT3 P40763 1/20 0.33
NPC1 O15118 1/20 0.33
CYP24A1 Q07973 1/20 0.32
HTR2A P28223 1/20 0.32
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30786179 0.93 PSMD10 (0.40) CA1CA9CA12CA2CNR2
SCHEMBL121411 0.84 CA1 (0.40) CA1CA9CA12CA2L3MBTL1
SCHEMBL17023777 0.83 CA1 (0.39) CA1CA9CA12CA2L3MBTL1
SCHEMBL30233639 0.81 DAO (0.41) CA1CA9CA12CA2L3MBTL1
SCHEMBL29226625 0.81 DAO (0.41) CA1CA9CA12CA2L3MBTL1
SCHEMBL18289524 0.80 CA1 (0.50) CA1CA9CA12CA2CNR2
SCHEMBL6906905 0.80 CA1 (0.50) CA1CA9CA12CA2CNR2
SCHEMBL29038057 0.77 CA1 (0.39) CA1CA9CA12CA2L3MBTL1
SCHEMBL4316004 0.75 HRH3 (0.44) CA1CA9CA12CA2L3MBTL1
SCHEMBL30292889 0.75 HRH3 (0.44) CA1CA9CA12CA2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260049071-A1 PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF BEYANG THERAPEUTICS CO LTD (CN) 2026-02-19 US disclosed
EP-4556466-A1 PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF Beyang Therapeutics Co., Ltd. (CN) 2025-05-21 EP disclosed
WO-2025082316-A1 OPHTHALMIC FORMATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF 苏州必扬医药科技有限公司 2025-04-24 WO disclosed
WO-2024032584-A1 PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF 苏州必扬医药科技有限公司 2024-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049071-A1 PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF KDR, FLT1, ERBB2 CA1 3348/4885CA9 1154/4885CA12 2521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.