Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.50 |
| ▸ | CA2 | P00918 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18289524 | 1.00 | CA1 (0.50) | CA1CA2ALDH1A1KMT2AMEN1 | |
| SCHEMBL948326 | 0.92 | CNR2 (0.56) | CA1CA2ALDH1A1KMT2AMEN1 | |
| SCHEMBL31757240 | 0.92 | CA1 (0.48) | CA1CA2ALDH1A1KMT2AMEN1 | |
| SCHEMBL21524969 | 0.92 | CA1 (0.48) | CA1CA2ALDH1A1KMT2AMEN1 | |
| SCHEMBL4432596 | 0.92 | CA1 (0.49) | CA1CA2ALDH1A1KMT2AMEN1 | |
| SCHEMBL7882874 | 0.92 | CA1 (0.44) | CA1CA2ALDH1A1KMT2AMEN1 | |
| SCHEMBL828951 | 0.92 | EGFR (0.47) | CA1CA2ALDH1A1KMT2AMEN1 | |
| SCHEMBL5351657 | 0.92 | CA1 (0.51) | CA1CA2ALDH1A1KMT2AMEN1 | |
| SCHEMBL241683 | 0.91 | CA9 (0.54) | CA1CA2ALDH1A1CA9CA12 | |
| SCHEMBL6803332 | 0.91 | ALDH1A1 (0.55) | ALDH1A1KMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677324-B1 | MIXTURE INCLUDES 7A-(E-AMINOALKYL)-ESTRATRIENE; HORMONE REPLACEMENT THERAPY; MENOPAUSE | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-01-13 | — | — | US | disclosed |
| EP-1203771-A1 | REMEDIES OR PREVENTIVES FOR FREQUENT URINATION OR URINARY INCONTINENCE | TORAY INDUSTRIES, INC. (JP) | 2002-05-08 | — | — | EP | disclosed |
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | disclosed |