Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30786228 | 0.82 | PDCD1 (0.37) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31517051 | 0.78 | KDR (0.42) | CYP4F2CYP4A11NPC1 | |
| SCHEMBL31475221 | 0.70 | PRKCQ (0.34) | CYP4F2CYP4A11 | |
| SCHEMBL11969974 | 0.66 | POLB (0.36) | CYP4F2CYP4A11MAP3K5PDE10A | |
| SCHEMBL5026596 | 0.66 | CYP1A2 (0.41) | MAP3K5PDE10ACYP2C19 | |
| SCHEMBL17846577 | 0.63 | MEN1 (0.53) | SMN1; SMN2 | |
| SCHEMBL18426399 | 0.63 | TSHR (0.43) | — | |
| SCHEMBL29705188 | 0.63 | FGFR1 (0.38) | CYP4F2CYP4A11NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18198891 | 0.63 | FGFR1 (0.38) | CYP4F2CYP4A11NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2489275 | 0.63 | NPSR1 (0.48) | NPC1RAB9ASMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024032584-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | 苏州必扬医药科技有限公司 | 2024-02-15 | — | — | WO | disclosed |