Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NMT1 | P30419 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436999 | 1.00 | CA12 (0.50) | CA12CA1MMP8MAPTTDP1 | |
| SCHEMBL29173167 | 1.00 | CA12 (0.50) | CA12CA1MMP8MAPTTDP1 | |
| SCHEMBL30644158 | 0.88 | PKM (0.57) | CA12CA1MAPTPOLBALDH1A1 | |
| SCHEMBL1355021 | 0.84 | SLC7A5 (0.53) | MAPTTDP1SMN1; SMN2PTGS2ALDH1A1 | |
| SCHEMBL7089012 | 0.83 | CA12 (0.47) | CA12CA1MAPTTDP1HPGD | |
| SCHEMBL16057214 | 0.83 | CA12 (0.47) | CA12CA1MAPTTDP1HPGD | |
| SCHEMBL7028109 | 0.83 | CA12 (0.47) | CA12CA1MAPTTDP1HPGD | |
| SCHEMBL33927 | 0.83 | TDP1 (0.56) | CA12MAPTTDP1POLBHPGD | |
| SCHEMBL1331551 | 0.83 | TDP1 (0.56) | CA12MAPTTDP1POLBHPGD | |
| SCHEMBL33928 | 0.83 | TDP1 (0.56) | CA12MAPTTDP1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154960-A | Amino acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | claimed |
| CN-115920000-B | Modulators of complement activity | RA制药公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-119823223-A | Apelin peptide energy macrocycle and application thereof | SOCPRA健康与人文科学有限公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-113396218-B | Engineered transaminase polypeptides | 科德克希思公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-118829646-A | Apelin peptide energy macrocycle and application thereof | SOCPRA健康与人文科学有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-118812647-A | Novel insect short neuropeptide sNPF analogue and application thereof | 四川轻化工大学 | 2024-10-22 | — | — | CN | disclosed |
| CN-117624307-A | Process for preparing cyclic organic compounds | 中外制药株式会社 | 2024-03-01 | — | — | CN | disclosed |
| EP-4136102-A1 | LONG ACTING PEPTIDE TYROSINE TYROSINE (PYY) ANALOGS AND METHODS OF USE | I2O Therapeutics, Inc. (US) | 2023-02-22 | — | — | EP | disclosed |
| WO-2021212023-A1 | LONG ACTING PEPTIDE TYROSINE TYROSINE (PYY) ANALOGS AND METHODS OF USE | INTARCIA THERAPEUTICS, INC. (US) | 2021-10-21 | — | — | WO | disclosed |
| US-9809706-B2 | Racemic drug resolution using polymer supported chiral selector | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-11-07 | — | — | US | disclosed |
| US-5721213-A | Peptides, active as inhibitors of platelet aggregation | NIPPON STEEL CORPORATION (JP) | 1998-02-24 | — | — | US | disclosed |
| EP-0796270-A2 | PEPTIDE COMPOUNDS FOR PREVENTION AND/OR TREATMENT OF NO-MEDIATED DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-24 | — | — | EP | disclosed |
| EP-0721468-A1 | NOVEL PEPTIDE, ACTIVE AS INHIBITORS OF PLATELET AGGREGATION | NIPPON STEEL CORPORATION (JP) | 1996-07-17 | — | — | EP | disclosed |
| US-5494672-A | HAVING SEQUENCE CORRESPONDING TO C-TERMINAL PORTION OF THE PSEUDOMONAS AERUGINOSA PILIN PROTEIN; VACCINE | S.P.I. SYNTHETIC PEPTIDES INCORPORATED (CA) | 1996-02-27 | — | — | US | disclosed |
| WO-1995009185-A1 | NOVEL PEPTIDE, ACTIVE AS INHIBITORS OF PLATELET AGGREGATION | NIPPON STEEL CORPORATION (JP) | 1995-04-06 | — | — | WO | disclosed |
| US-5401783-A | Adhesion-promoting agents incorporating polyvalent cations | AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) | 1995-03-28 | — | — | US | disclosed |
| US-5270351-A | Adhesion-promoting agents incorporating polyvalent cations | AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) | 1993-12-14 | — | — | US | disclosed |
| EP-0567470-A1 | PSEUDOMONAS PEPTIDE COMPOSITION AND METHOD FOR PRODUCING THE SAME | S.P.I. SYNTHETIC PEPTIDES INCORPORATED (CA) | 1993-11-03 | — | — | EP | disclosed |
| WO-1992012169-A1 | PSEUDOMONAS PEPTIDE COMPOSITION AND METHOD FOR PRODUCING THE SAME | S.P.I. SYNTHETIC PEPTIDES INCORPORATED (CA) | 1992-07-23 | — | — | WO | disclosed |
| EP-0331404-A2 | Method for producing tropane alkaloid | SEITAIKINOU RIYOU KAGAKUHIN SHINSEIZOUGIJUTSU KENKYU KUMIAI (JP) | 1989-09-06 | — | — | EP | disclosed |