Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.69 |
| ▸ | MAOA | P21397 | 7/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11798994 | 0.95 | MAOB (0.67) | MAOBMAOANPC1RAB9ATSHR | |
| SCHEMBL11798944 | 0.93 | MAOB (0.65) | MAOBMAOANPC1RAB9ATSHR | |
| SCHEMBL11799016 | 0.93 | MAOB (0.65) | MAOBMAOANPC1RAB9ATSHR | |
| SCHEMBL11798933 | 0.93 | MAOB (0.65) | MAOBMAOANPC1RAB9ATSHR | |
| SCHEMBL5725730 | 0.91 | MAOB (0.71) | MAOBMAOANPC1RAB9ATSHR | |
| SCHEMBL108114 | 0.89 | MAOB (0.74) | MAOBMAOANPC1RAB9ATSHR | |
| SCHEMBL11802724 | 0.87 | MAOB (0.72) | MAOBMAOANPC1RAB9ATSHR | |
| SCHEMBL107322 | 0.87 | MAOB (0.83) | MAOBMAOANPC1RAB9ATSHR | |
| SCHEMBL7236239 | 0.84 | MAOB (0.71) | MAOBMAOANPC1RAB9ATSHR | |
| SCHEMBL984460 | 0.84 | MAOB (0.68) | MAOBMAOANPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11189593-A | — | — | None | — | — | JP | disclosed |
| EP-4400504-A1 | THIOPHENE RING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences (CN) | 2024-07-17 | — | — | EP | disclosed |
| US-7842688-B2 | Organic compounds | NOVARTIS PHARMA AG (CH) | 2010-11-30 | — | — | US | disclosed |
| US-7790715-B2 | Organic compounds | NOVARTIS AG (CH) | 2010-09-07 | — | — | US | disclosed |
| US-20090012055-A1 | Organic compounds | HEROLD PETER | 2009-01-08 | — | — | US | disclosed |
| EP-1961752-A2 | Piperidine Compounds | Speedel Experimenta AG (CH) | 2008-08-27 | — | — | EP | disclosed |
| US-7189741-B2 | Indolylpiperidine derivatives as antihistaminic and antiallergic agents | ALMIRALL PRODESFARMA S.A. (ES) | 2007-03-13 | — | — | US | disclosed |
| US-20070010511-A1 | Organic compounds | NOVARTIS PHARMA AG (CH) | 2007-01-11 | — | — | US | disclosed |
| EP-1670760-A1 | ORGANIC COMPOUNDS | Speedel Experimenta AG (CH) | 2006-06-21 | — | — | EP | disclosed |
| EP-1330453-B1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | ALMIRALL PRODESFARMA SA (ES) | 2006-03-29 | — | — | EP | disclosed |
| WO-2005061457-A1 | ORGANIC COMPOUNDS | SPEEDEL EXPERIMENTA AG (CH) | 2005-07-07 | — | — | WO | disclosed |
| US-20040116471-A1 | Indolylpiperidine derivatives as antihistaminic aand antiallergic agents | ALMIRALL PRODESFARMA S.A. (ES) | 2004-06-17 | — | — | US | disclosed |
| JP-H11189593-A | 2-(PIPERIDYLALKYLCARBONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVE OR ITS SALT | YAMANOUCHI PHARMACEUT CO LTD | 1999-07-13 | — | — | JP | disclosed |
| US-4684739-A | HYPOTENSIVE AGENTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1987-08-04 | — | — | US | disclosed |
| EP-0054304-B1 | ALKYLENEDIOXYBENZENE DERIVATIVES, ACID ADDITION SALTS THEREOF AND A METHOD FOR THEIR PREPARATION | MITSUBISHI KASEI CORPORATION (JP) | 1984-08-15 | — | — | EP | disclosed |
| EP-0054304-A1 | Alkylenedioxybenzene derivatives, acid addition salts thereof and a method for their preparation | MITSUBISHI KASEI CORPORATION (JP) | 1982-06-23 | — | — | EP | disclosed |
| US-3933837-A | 3,4-Methylenedioxyphenoxy-alkyl diketones and keto-esters | STERLING DRUG INC. (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012055-A1 | Organic compounds | REN, ACE, ACE2 | MAOB 43/4885MAOA 85/4885NPC1 794/4885 |
| US-20070010511-A1 | Organic compounds | REN, ACE, ACE2 | MAOB 43/4885MAOA 85/4885NPC1 794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.