Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 19/20 | 1.00 |
| ▸ | PRKAB1 | Q9Y478 | 19/20 | 1.00 |
| ▸ | PRKAA2 | P54646 | 16/20 | 1.00 |
| ▸ | PRKAA1 | Q13131 | 9/20 | 1.00 |
| ▸ | PRKAB2 | O43741 | 4/20 | 1.00 |
| ▸ | PRKAG3 | Q9UGI9 | 4/20 | 1.00 |
| ▸ | PRKAG2 | Q9UGJ0 | 4/20 | 1.00 |
| ▸ | TFDP2 | Q14188 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29376061 | 1.00 | PRKAG1 (1.00) | PRKAG1PRKAB1PRKAA2PRKAA1PRKAB2 | |
| SCHEMBL3036566 | 1.00 | PRKAG1 (1.00) | PRKAG1PRKAB1PRKAA2PRKAA1PRKAB2 | |
| SCHEMBL13437301 | 0.98 | PRKAG1 (0.96) | PRKAG1PRKAB1PRKAA2PRKAA1PRKAB2 | |
| SCHEMBL3481470 | 0.94 | PRKAG1 (0.89) | PRKAG1PRKAB1PRKAA2PRKAA1PRKAB2 | |
| SCHEMBL3481025 | 0.94 | PRKAG1 (0.89) | PRKAG1PRKAB1PRKAA2PRKAA1PRKAB2 | |
| SCHEMBL3481698 | 0.94 | PRKAG1 (0.89) | PRKAG1PRKAB1PRKAA2PRKAA1PRKAB2 | |
| SCHEMBL3481331 | 0.94 | PRKAG1 (0.89) | PRKAG1PRKAB1PRKAA2PRKAA1PRKAB2 | |
| SCHEMBL3481329 | 0.94 | PRKAG1 (0.88) | PRKAG1PRKAB1PRKAA2PRKAA1PRKAB2 | |
| SCHEMBL3481232 | 0.93 | PRKAG1 (0.87) | PRKAG1PRKAB1PRKAA2PRKAA1PRKAB2 | |
| SCHEMBL29659650 | 0.93 | PRKAG1 (0.87) | PRKAG1PRKAB1PRKAA2PRKAA1PRKAB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117243950-A | Application of MK-3903 in preparation of medicines for preventing and/or treating ischemic heart disease | 首都医科大学附属北京朝阳医院 | 2023-12-19 | — | — | CN | disclosed |