Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18935939 | 0.86 | TLR9 (0.55) | SMN1; SMN2KDM4EALDH1A1HPGDTLR9 | |
| SCHEMBL10590678 | 0.85 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL23748384 | 0.84 | HDAC6 (0.56) | CETPSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL30789017 | 0.84 | HDAC6 (0.56) | CETPSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL25026542 | 0.83 | HDAC3 (0.60) | CETPSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL23748387 | 0.82 | SMN1; SMN2 (0.71) | SMN1; SMN2KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL2245453 | 0.81 | NPC1 (0.67) | SMN1; SMN2KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL17199136 | 0.81 | NPC1 (0.74) | SMN1; SMN2KDM4EALDH1A1HPGDNFKB1 | |
| SCHEMBL14243239 | 0.81 | HDAC6 (0.53) | SMN1; SMN2KDM4EALDH1A1HPGDTLR9 | |
| SCHEMBL8740136 | 0.81 | ESR1 (0.74) | TLR9HDAC6HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195084-B | Benzoxazoles and related compounds useful as modulators of chaperone mediated autophagy | 阿尔伯爱因斯坦医学院 | 2024-04-09 | — | — | CN | claimed |
| CN-113195084-B | Benzoxazoles and related compounds useful as modulators of chaperone mediated autophagy | 阿尔伯爱因斯坦医学院 | 2024-04-09 | — | — | CN | disclosed |