Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 3/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CHUK | O15111 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30789586 | 0.93 | BCL6 (0.45) | BCL6CTSSMAPTALDH1A1MAPK1 | |
| SCHEMBL30789711 | 0.92 | CUL4A (0.46) | BCL6CTSSMAPTALDH1A1MAPK1 | |
| SCHEMBL30789432 | 0.85 | JAK2 (0.39) | BCL6CTSSMAPTALDH1A1MAPK1 | |
| SCHEMBL30789637 | 0.78 | PRKCQ (0.45) | CTSSMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL30789632 | 0.78 | PRKCQ (0.45) | CTSSMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL30789448 | 0.78 | CUL4A (0.39) | MAPTALDH1A1MAPK1POLBCUL4A | |
| SCHEMBL30789741 | 0.71 | CUL4A (0.44) | BCL6MAPTALDH1A1CUL4ACYP1A2 | |
| SCHEMBL30789385 | 0.71 | CUL4A (0.48) | BCL6MAPTALDH1A1POLBCUL4A | |
| SCHEMBL25407976 | 0.67 | POLB (0.34) | MAPTALDH1A1MAPK1POLBTDP1 | |
| SCHEMBL5822677 | 0.65 | MAPT (0.55) | MAPTALDH1A1MAPK1POLBCUL4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587124-A1 | POLYCYCLIC QUINAZOLINES FOR INHIBITION OF ERBB2 | Enliven Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059558-A1 | POLYCYCLIC QUINAZOLINES FOR INHIBITION OF ERBB2 | ENLIVEN INC. (US) | 2024-03-21 | — | — | WO | disclosed |