Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 1/20 | 0.44 |
| ▸ | CHUK | O15111 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | BCL6 | P41182 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30789385 | 0.97 | CUL4A (0.48) | CUL4ACHUKMAPTCYP1A2CYP3A4 | |
| SCHEMBL30789448 | 0.93 | CUL4A (0.39) | CUL4ACHUKMAPTCYP1A2CYP3A4 | |
| SCHEMBL30789621 | 0.84 | KMT2A (0.35) | CUL4AMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30789586 | 0.79 | BCL6 (0.45) | CUL4ACHUKMAPTCYP1A2CYP3A4 | |
| SCHEMBL30789711 | 0.76 | CUL4A (0.46) | CUL4ACHUKMAPTCYP1A2CYP3A4 | |
| SCHEMBL17111542 | 0.75 | CUL4A (0.50) | CUL4AMAPTCCNE2CDK4CCND1 | |
| SCHEMBL17111487 | 0.75 | CUL4A (0.50) | CUL4AMAPTCCNE2CDK4CCND1 | |
| SCHEMBL30789738 | 0.71 | BCL6 (0.38) | CUL4ACHUKMAPTCYP1A2CYP3A4 | |
| SCHEMBL29662453 | 0.71 | SMN1; SMN2 (0.37) | CUL4AMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL30789707 | 0.69 | MAPT (0.41) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587124-A1 | POLYCYCLIC QUINAZOLINES FOR INHIBITION OF ERBB2 | Enliven Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059558-A1 | POLYCYCLIC QUINAZOLINES FOR INHIBITION OF ERBB2 | ENLIVEN INC. (US) | 2024-03-21 | — | — | WO | disclosed |