Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 13/20 | 0.51 |
| ▸ | HTR2B | P41595 | 13/20 | 0.51 |
| ▸ | HTR2A | P28223 | 11/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30790625 | 0.92 | CRBN (0.47) | HTR2CHTR2BHTR2APARP1CXCR4 | |
| SCHEMBL30459092 | 0.91 | HTR2C (0.47) | HTR2CHTR2BHTR2APARP1IKZF2 | |
| SCHEMBL30459017 | 0.91 | HTR2C (0.46) | HTR2CHTR2BHTR2APARP1MEN1 | |
| SCHEMBL30459129 | 0.87 | HTR2B (0.44) | HTR2CHTR2BHTR2APARP1IKZF2 | |
| SCHEMBL30458379 | 0.87 | HTR2B (0.44) | HTR2CHTR2BHTR2APARP1IKZF2 | |
| SCHEMBL30459711 | 0.86 | HTR2B (0.47) | HTR2CHTR2BHTR2APARP1 | |
| SCHEMBL30459947 | 0.85 | HTR2B (0.46) | HTR2CHTR2BHTR2APARP1 | |
| SCHEMBL23880785 | 0.85 | IKZF2 (0.51) | HTR2CHTR2BHTR2AIKZF2 | |
| SCHEMBL25235039 | 0.84 | HTR2B (0.49) | HTR2CHTR2BHTR2APARP1 | |
| SCHEMBL2333387 | 0.84 | HTR2B (0.49) | HTR2CHTR2BHTR2APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024032689-A1 | COMPOUND BASED ON ISOINDOLINE-SUBSTITUTED GLUTARIMIDE BACKBONE AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-02-15 | — | — | WO | disclosed |