Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.46 |
| ▸ | HTR2B | P41595 | 11/20 | 0.46 |
| ▸ | HTR2A | P28223 | 9/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | IKZF2 | Q9UKS7 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30790468 | 0.91 | HTR2C (0.51) | HTR2CHTR2BHTR2APARP1IKZF2 | |
| SCHEMBL30459092 | 0.88 | HTR2C (0.47) | HTR2CHTR2BHTR2APARP1IKZF2 | |
| SCHEMBL30459711 | 0.85 | HTR2B (0.47) | HTR2CHTR2BHTR2APARP1 | |
| SCHEMBL30458379 | 0.84 | HTR2B (0.44) | HTR2CHTR2BHTR2APARP1IKZF2 | |
| SCHEMBL30459129 | 0.84 | HTR2B (0.44) | HTR2CHTR2BHTR2APARP1IKZF2 | |
| SCHEMBL30459947 | 0.84 | HTR2B (0.46) | HTR2CHTR2BHTR2APARP1 | |
| SCHEMBL30790625 | 0.83 | CRBN (0.47) | HTR2CHTR2BHTR2APARP1MEN1 | |
| SCHEMBL30789997 | 0.82 | HTR2A (0.40) | HTR2CHTR2BHTR2APARP1KMT2A | |
| SCHEMBL23880785 | 0.82 | IKZF2 (0.51) | HTR2CHTR2BHTR2AIKZF2IKZF1 | |
| SCHEMBL2333387 | 0.82 | HTR2B (0.49) | HTR2CHTR2BHTR2APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | claimed |