Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 12/20 | 0.34 |
| ▸ | DRD3 | P35462 | 12/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GPR6 | P46095 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16091552 | 1.00 | MAPK1 (0.34) | MAPK1DRD2DRD3KDM4EGAA | |
| SCHEMBL16040435 | 1.00 | MAPK1 (0.34) | MAPK1DRD2DRD3KDM4EGAA | |
| SCHEMBL16079665 | 0.96 | MAPK1 (0.34) | MAPK1DRD2DRD3KDM4EGAA | |
| SCHEMBL17750693 | 0.88 | DRD2 (0.35) | MAPK1DRD2DRD3KDM4EGAA | |
| SCHEMBL16040755 | 0.85 | MAPK1 (0.43) | MAPK1DRD2DRD3GPR6 | |
| SCHEMBL16079599 | 0.85 | MAPK1 (0.43) | MAPK1DRD2DRD3GPR6 | |
| SCHEMBL30790689 | 0.85 | MAPK1 (0.43) | MAPK1DRD2DRD3GPR6 | |
| SCHEMBL16040749 | 0.85 | MAPK1 (0.43) | MAPK1DRD2DRD3GPR6 | |
| SCHEMBL16088307 | 0.83 | — | — | |
| SCHEMBL16038800 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111741955-B | DNA-PK inhibitors | 沃泰克斯药物股份有限公司 | 2024-02-23 | — | — | CN | disclosed |