Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 10/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 9/20 | 0.37 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16040024 | 1.00 | SYK (0.43) | SYKKDRTBK1IKBKELRRK2 | |
| SCHEMBL16038633 | 1.00 | SYK (0.43) | SYKKDRTBK1IKBKELRRK2 | |
| SCHEMBL29578990 | 1.00 | SYK (0.43) | SYKKDRTBK1IKBKELRRK2 | |
| SCHEMBL17750250 | 0.89 | SYK (0.39) | SYKKDRTBK1IKBKEKCNH2 | |
| SCHEMBL17750235 | 0.88 | SYK (0.50) | SYKKDRTBK1IKBKELRRK2 | |
| SCHEMBL16040973 | 0.87 | SYK (0.38) | SYKKDRTBK1IKBKELRRK2 | |
| SCHEMBL16040412 | 0.87 | SYK (0.38) | SYKKDRTBK1IKBKELRRK2 | |
| SCHEMBL16040414 | 0.87 | SYK (0.38) | SYKKDRTBK1IKBKELRRK2 | |
| SCHEMBL17750256 | 0.86 | PRKDC (0.44) | SYKKDRTBK1IKBKE | |
| SCHEMBL17750498 | 0.85 | TBK1 (0.39) | SYKKDRTBK1IKBKELRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111741955-B | DNA-PK inhibitors | 沃泰克斯药物股份有限公司 | 2024-02-23 | — | — | CN | disclosed |