SCHEMBL30790879

SCHEMBL30790879

CC(C)C(C)C(=O)N1CCc2nc(N3C4CCC3CNC4)ccc2C1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 3/20 0.34
CDK2 P24941 3/20 0.34
CDK6 Q00534 3/20 0.34
HSP90AA1 P07900 12/20 0.34
HSP90B1 P14625 4/20 0.34
CDK1 P06493 1/20 0.34
CDK7 P50613 1/20 0.34
CDK9 P50750 1/20 0.34
NAMPT P43490 2/20 0.33
ACE P12821 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30790816 0.90 DPP8 (0.36) HSP90AA1HSP90B1NAMPT
SCHEMBL31484847 0.85 CDK4 (0.33) CDK4CDK2CDK6HSP90AA1HSP90B1
SCHEMBL30790814 0.84 SYK (0.36) HSP90AA1HSP90B1NAMPT
SCHEMBL31484851 0.84 SYK (0.36) HSP90AA1HSP90B1NAMPT
SCHEMBL30790842 0.84 PDE10A (0.35) CDK4CDK2CDK6HSP90AA1HSP90B1
SCHEMBL30790869 0.84 DPP8 (0.38) CDK4CDK2CDK6HSP90AA1HSP90B1
SCHEMBL30790838 0.82 KCNH2 (0.38) CDK4HSP90AA1HSP90B1
SCHEMBL30790817 0.81 KEAP1 (0.47)
SCHEMBL30790826 0.81 MAP3K5 (0.36) CDK4CDK2CDK6HSP90AA1CDK1
SCHEMBL30790810 0.80 FLT3 (0.38) CDK4CDK2CDK6CDK1CDK7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001876-A1 Compounds and Their Use as PDE4 Activators MIRONID LIMITED (GB) 2026-01-01 US claimed
EP-4572761-A1 COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS Mironid Limited (GB) 2025-06-25 EP claimed
WO-2024038129-A1 COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS MIRONID LIMITED (GB) 2024-02-22 WO claimed
US-20260001876-A1 Compounds and Their Use as PDE4 Activators MIRONID LIMITED (GB) 2026-01-01 US disclosed
EP-4572761-A1 COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS Mironid Limited (GB) 2025-06-25 EP disclosed
WO-2024038129-A1 COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS MIRONID LIMITED (GB) 2024-02-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001876-A1 Compounds and Their Use as PDE4 Activators PDE4A, PDE4B, PDE7A CDK4 1396/4885CDK2 1728/4885CDK6 1680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.