Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 1.00 |
| ▸ | MAOB | P27338 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MIF | P14174 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3081130 | 0.80 | GPR35 (0.67) | GPR35KDM4ECA9ALDH1A1MIF | |
| SCHEMBL15842406 | 0.78 | GPR35 (0.65) | GPR35MAOBKDM4ECA9ALDH1A1 | |
| SCHEMBL622794 | 0.77 | KDM4E (0.64) | GPR35MAOBKDM4ECA9ALDH1A1 | |
| SCHEMBL6836551 | 0.76 | GLA (0.78) | GPR35MAOBKDM4ECA9ALDH1A1 | |
| SCHEMBL29082332 | 0.75 | GPR35 (0.60) | GPR35MAOBKDM4ECA9ALDH1A1 | |
| SCHEMBL7023546 | 0.74 | GPR35 (0.62) | GPR35MAOBCA9CA1CA2 | |
| SCHEMBL11578348 | 0.74 | MAOB (0.68) | GPR35MAOBKDM4ECA9ALDH1A1 | |
| SCHEMBL30550392 | 0.74 | MAOB (0.68) | GPR35MAOBKDM4ECA9ALDH1A1 | |
| SCHEMBL1618338 | 0.74 | MAOB (0.68) | GPR35MAOBKDM4ECA9ALDH1A1 | |
| SCHEMBL7971600 | 0.74 | MAOB (0.68) | GPR35MAOBKDM4ECA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108069929-B | 3-substituted coumarin derivative and application thereof, and GPR35 receptor agonist | 中国科学院大连化学物理研究所 | 2021-06-15 | — | — | CN | claimed |
| CN-108069929-B | 3-substituted coumarin derivative and application thereof, and GPR35 receptor agonist | 中国科学院大连化学物理研究所 | 2021-06-15 | — | — | CN | disclosed |
| EP-2825261-A1 | POLYPEPTIDES AND THEIR USE | Novabiotics Limited (GB) | 2015-01-21 | — | — | EP | disclosed |
| US-20140155321-A1 | Polypeptides and Their Use | NOVABIOTICS LIMITED (GB) | 2014-06-05 | — | — | US | disclosed |
| WO-2013136040-A1 | POLYPEPTIDES AND THEIR USE | NOVABIOTICS LIMITED (GB) | 2013-09-19 | — | — | WO | disclosed |
| US-20100267653-A1 | USE OF COUMARIN DERIVATIVES IN ANTIFUNGAL THERAPY | NOVABIOTICS LIMITED (GB) | 2010-10-21 | — | — | US | disclosed |
| CN-101501015-A | Use of coumarin derivatives in antifungal therapy | NOVABIOTICS LTD (GB) | 2009-08-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267653-A1 | USE OF COUMARIN DERIVATIVES IN ANTIFUNGAL THERAPY | DPM1, XPO5, NISCH | GPR35 4086/4885MAOB 3597/4885KDM4E 3277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.