Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.37 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.37 |
| ▸ | KCNK18 | Q7Z418 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CCR4 | P51679 | 1/20 | 0.37 |
| ▸ | ULK1 | O75385 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | RXRB | P28702 | 2/20 | 0.34 |
| ▸ | RXRG | P48443 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23356090 | 1.00 | NISCH (0.42) | NISCHEGFRZAP70MEN1KMT2A | |
| SCHEMBL23356095 | 0.88 | NISCH (0.43) | NISCHEGFRZAP70MEN1KMT2A | |
| SCHEMBL30791217 | 0.88 | NISCH (0.43) | NISCHEGFRZAP70MEN1KMT2A | |
| SCHEMBL30791210 | 0.88 | NISCH (0.42) | NISCHEGFRZAP70MEN1KMT2A | |
| SCHEMBL23356021 | 0.88 | NISCH (0.42) | NISCHEGFRZAP70MEN1KMT2A | |
| SCHEMBL23356047 | 0.87 | ALDH1A1 (0.42) | NISCHEGFRZAP70MEN1KMT2A | |
| SCHEMBL30791290 | 0.87 | ALDH1A1 (0.42) | NISCHEGFRZAP70MEN1KMT2A | |
| SCHEMBL23356015 | 0.87 | GSK3A (0.40) | NISCHEGFRZAP70MEN1KMT2A | |
| SCHEMBL30791254 | 0.87 | GSK3A (0.40) | NISCHEGFRZAP70MEN1KMT2A | |
| SCHEMBL23356028 | 0.87 | EGFR (0.46) | NISCHEGFRZAP70MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313232-B | Novel heterocyclic derivatives | JW中外制药公司 | 2024-03-08 | — | — | CN | disclosed |