Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 3/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.42 |
| ▸ | CBLB | Q13191 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 5/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.32 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29920812 | 0.81 | CBLB (0.43) | CBLB | |
| SCHEMBL24818748 | 0.81 | CBLB (0.43) | CBLB | |
| SCHEMBL27085815 | 0.80 | CBLB (0.47) | CBLBPDE2APDE10APDE4APDE4B | |
| SCHEMBL24818750 | 0.78 | CBLB (0.45) | CBLBGSK3BDYRK1A | |
| SCHEMBL30792029 | 0.77 | CBLB (0.44) | CBLBGSK3BDYRK1A | |
| SCHEMBL29193191 | 0.76 | CBLB (0.42) | CBLBGSK3BDYRK1A | |
| SCHEMBL29189939 | 0.76 | CBLB (0.36) | CBLB | |
| SCHEMBL29920134 | 0.74 | CBLB (0.42) | CBLB | |
| SCHEMBL30956963 | 0.72 | CBLB (0.42) | CBLBPDE10APCSK9GSK3BDYRK1A | |
| SCHEMBL27308766 | 0.72 | CBLB (0.42) | CBLBPDE10APCSK9GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |