Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 4/20 | 0.43 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
| ▸ | ROS1 | P08922 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29920812 | 1.00 | CBLB (0.43) | CBLBBDKRB2ROS1MEN1KMT2A | |
| SCHEMBL27308766 | 0.89 | CBLB (0.42) | CBLBBDKRB2ROS1 | |
| SCHEMBL30956963 | 0.89 | CBLB (0.42) | CBLBBDKRB2ROS1 | |
| SCHEMBL24818754 | 0.86 | CBLB (0.48) | CBLBBDKRB2 | |
| SCHEMBL24818750 | 0.83 | CBLB (0.45) | CBLBROS1 | |
| SCHEMBL29189939 | 0.83 | CBLB (0.36) | CBLB | |
| SCHEMBL30792029 | 0.83 | CBLB (0.44) | CBLBROS1 | |
| SCHEMBL30792122 | 0.81 | MAPK13 (0.42) | CBLB | |
| SCHEMBL29920612 | 0.81 | BDKRB2 (0.36) | CBLBBDKRB2PGK1 | |
| SCHEMBL27086183 | 0.81 | BDKRB2 (0.36) | CBLBBDKRB2PGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-117858707-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| EP-4319756-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |