Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29189985 | 0.82 | ALDH1A1 (0.50) | TSHRALDH1A1CYP3A4ARTDP1 | |
| SCHEMBL27903845 | 0.81 | HSD17B10 (0.41) | TSHRALDH1A1CYP3A4RECQLHSD17B10 | |
| SCHEMBL28179841 | 0.81 | TSHR (0.50) | TSHRALDH1A1CYP3A4RECQLHSD17B10 | |
| SCHEMBL30153092 | 0.81 | ALDH1A1 (0.45) | TSHRALDH1A1CYP3A4ARTDP1 | |
| SCHEMBL27963143 | 0.79 | TSHR (0.47) | TSHRALDH1A1CYP3A4RECQLHSD17B10 | |
| SCHEMBL30152516 | 0.79 | ALDH1A1 (0.47) | TSHRALDH1A1CYP3A4ARTDP1 | |
| SCHEMBL30152985 | 0.79 | TDP1 (0.45) | ALDH1A1CYP3A4HSD17B10ARTDP1 | |
| SCHEMBL2056614 | 0.77 | TSHR (0.57) | TSHRALDH1A1CYP3A4RECQLHSD17B10 | |
| SCHEMBL27601632 | 0.77 | AR (0.43) | TSHRALDH1A1CYP3A4RECQLHSD17B10 | |
| SCHEMBL27438856 | 0.77 | ALDH1A1 (0.49) | TSHRALDH1A1CYP3A4RECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |