Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 16/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CFTR | P13569 | 1/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30792253 | 0.96 | PI4KB (0.61) | PI4KBPIK3CDPIK3CG | |
| SCHEMBL30792278 | 0.93 | PI4KB (0.63) | PI4KBPIK3CDPIK3CG | |
| SCHEMBL29265063 | 0.92 | PIK3CD (0.59) | PI4KBPIK3CDPIK3CG | |
| SCHEMBL29180145 | 0.91 | PI4KB (0.52) | PI4KBMEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL29265071 | 0.90 | PI4KB (0.51) | PI4KBPIK3CDPIK3CG | |
| SCHEMBL29265070 | 0.90 | PI4KB (0.63) | PI4KBMEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL29265057 | 0.89 | PI4KB (0.64) | PI4KBPIK3CDPIK3CG | |
| SCHEMBL30792286 | 0.89 | PI4KB (0.62) | PI4KBPIK3CDPIK3CG | |
| SCHEMBL29265052 | 0.87 | PIK3CD (0.49) | PI4KBPIK3CDPIK3CG | |
| SCHEMBL30997394 | 0.86 | PI4KB (0.59) | PI4KBMEN1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117534631-B | Phenylthiazole amine PI4KIII beta inhibitor, preparation method, pharmaceutical composition and application thereof | 南京市鸿舜医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-117534631-A | Phenylthiazole amine PI4KIII beta inhibitor, preparation method, pharmaceutical composition and application thereof | 南京市鸿舜医药科技有限公司 | 2024-02-09 | — | — | CN | disclosed |