Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 18/20 | 0.63 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30792253 | 0.94 | PI4KB (0.61) | PI4KBPIK3CDPIK3CG | |
| SCHEMBL30792220 | 0.93 | PI4KB (0.60) | PI4KBPIK3CDPIK3CG | |
| SCHEMBL30792286 | 0.92 | PI4KB (0.62) | PI4KBPIK3CDPIK3CG | |
| SCHEMBL29180152 | 0.91 | PI4KB (0.54) | PI4KBPIK3CDPIK3CG | |
| SCHEMBL48498 | 0.87 | PIK3CD (0.72) | PI4KBPIK3CDPIK3CG | |
| SCHEMBL30997409 | 0.87 | PI4KB (0.62) | PI4KBPIK3CD | |
| SCHEMBL19303682 | 0.86 | PI4KB (0.75) | PI4KBPIK3CDPIK3CG | |
| SCHEMBL48560 | 0.86 | PI4KB (0.60) | PI4KBPIK3CDPIK3CG | |
| SCHEMBL29180153 | 0.86 | PI4KB (0.53) | PI4KBPIK3CDPIK3CG | |
| SCHEMBL22336563 | 0.85 | PI4KB (0.74) | PI4KBPIK3CDPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117534631-B | Phenylthiazole amine PI4KIII beta inhibitor, preparation method, pharmaceutical composition and application thereof | 南京市鸿舜医药科技有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-117534631-A | Phenylthiazole amine PI4KIII beta inhibitor, preparation method, pharmaceutical composition and application thereof | 南京市鸿舜医药科技有限公司 | 2024-02-09 | — | — | CN | claimed |
| CN-117534631-B | Phenylthiazole amine PI4KIII beta inhibitor, preparation method, pharmaceutical composition and application thereof | 南京市鸿舜医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-117534631-A | Phenylthiazole amine PI4KIII beta inhibitor, preparation method, pharmaceutical composition and application thereof | 南京市鸿舜医药科技有限公司 | 2024-02-09 | — | — | CN | disclosed |