SCHEMBL30792570

SCHEMBL30792570

CN1CCN(c2ccc(Oc3cc(CN4CC[C@@H]5C[C@@H]5CC4)cc(-c4cc(Cl)cc(Cl)c4)n3)cn2)CC1

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27032594 0.93 FURIN (0.65) FURIN
SCHEMBL30792571 0.89 FURIN (0.78) FURIN
SCHEMBL29927825 0.88 FURIN (0.81) FURIN
SCHEMBL21550674 0.88 FURIN (0.81) FURIN
SCHEMBL29928121 0.87 FURIN (0.67) FURIN
SCHEMBL21550841 0.87 FURIN (0.67) FURIN
SCHEMBL21550843 0.87 FURIN (0.67) FURIN
SCHEMBL27052572 0.87 FURIN (0.67) FURIN
SCHEMBL21550844 0.87 FURIN (0.67) FURIN
SCHEMBL27052587 0.87 FURIN (0.67) FURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3790871-B1 FURIN INHIBITORS GLAXOSMITHKLINE IP DEV LTD (GB) 2024-01-24 — — EP claimed
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