SCHEMBL3079282

SCHEMBL3079282

OCC(O)CNCc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.57
BCHE P06276 2/20 0.54
ALDH1A1 P00352 2/20 0.50
ANPEP P15144 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
LMNA P02545 1/20 0.49
KDM4E B2RXH2 1/20 0.48
MAOA P21397 1/20 0.45
THRB P10828 1/20 0.45
IDO1 P14902 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10533348 1.00 DNM1 (0.57) DNM1BCHEALDH1A1ANPEPCYP1A2
SCHEMBL893963 0.90 BCHE (0.63) DNM1BCHEALDH1A1ANPEPCYP1A2
SCHEMBL9168696 0.86 DNM1 (0.49) DNM1BCHEALDH1A1ANPEPCYP1A2
SCHEMBL14015727 0.84 DNM1 (0.57) DNM1BCHEALDH1A1ANPEPCYP1A2
SCHEMBL2919287 0.82 DNM1 (0.55) DNM1BCHEALDH1A1ANPEPCYP1A2
SCHEMBL19122419 0.82 DNM1 (0.55) DNM1BCHEALDH1A1ANPEPCYP1A2
SCHEMBL2305792 0.82 DNM1 (0.55) DNM1BCHEALDH1A1ANPEPCYP1A2
SCHEMBL2840755 0.82 DNM1 (0.55) DNM1BCHEALDH1A1ANPEPCYP1A2
SCHEMBL3029456 0.82 DNM1 (0.59) DNM1BCHEALDH1A1ANPEPCYP1A2
SCHEMBL14532283 0.82 DNM1 (0.55) DNM1BCHEALDH1A1ANPEPCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324707-A Synthesis method of (S) -6-hydroxymethyl-morpholin-3-one 西安宇特邦医药科技有限公司 2024-07-12 CN claimed
EP-0863875-B1 NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY HOFFMANN LA ROCHE (CH) 2003-06-04 EP claimed
EP-0863875-A1 NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY F. HOFFMANN-LA ROCHE AG (CH) 1998-09-16 EP claimed
WO-1997009311-A1 NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY F. HOFFMANN-LA ROCHE AG (CH) 1997-03-13 WO claimed
CN-117777048-B Preparation method of chiral 2-hydroxymethylmorpholine-4-carboxylic acid tert-butyl ester 上海科利生物医药有限公司 2024-09-20 CN disclosed
CN-118420543-A Tumor inhibitor targeting EP300 mutation and application thereof 上海美得诺瓦生物医药科技有限公司 2024-08-02 CN disclosed
CN-118324707-A Synthesis method of (S) -6-hydroxymethyl-morpholin-3-one 西安宇特邦医药科技有限公司 2024-07-12 CN disclosed
CN-117777048-A Preparation method of chiral 2-hydroxymethylmorpholine-4-carboxylic acid tert-butyl ester 上海科利生物医药有限公司 2024-03-29 CN disclosed
US-10808246-B2 Oligonucleotide-ligand conjugates and process for their preparation ALNYLAM PHARMACEUTICALS, INC. (US) 2020-10-20 US disclosed
CN-103525435-B Crystal aligning agent, the manufacture method of liquid crystal display cells, liquid crystal orienting film, liquid crystal display cells and polymer JSR株式会社 2016-09-14 CN disclosed
CN-103666487-B Crystal aligning agent, liquid crystal orienting film and liquid crystal display cells JSR株式会社 2016-08-24 CN disclosed
CN-103509563-B Light orientation crystal aligning agent, liquid crystal orienting film and manufacture method, liquid crystal display cells, compound and polymer JSR株式会社 2016-08-10 CN disclosed
US-4652563-A PYRIDAZINONES SUBSTITUTED WITH CYCLOPROPYLMETHOXYETHYL GROUP SMITH KLINE & FRENCH LABORATORIES LTD. (GB) 1987-03-24 US disclosed
WO-1986006368-A1 STEREOSELECTIVE PROCESS AND CHIRAL INTERMEDIATES FOR ARYLOXYDROPANOLAMINES SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1986-11-06 WO disclosed
EP-0168921-A2 Chemical compounds SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1986-01-22 EP disclosed
US-4410530-A CARDIO-SELECTIVE B-RECEPTOR BLOCKING AGENTS AND STIMULANTS CIBA-GEIGY CORPORATION (US) 1983-10-18 US disclosed
US-4195090-A ADRENERGIC BLOCKING AGENTS CIBA-GEIGY CORPORATION (US) 1980-03-25 US disclosed
US-4139623-A HYPOTENSIVE AGENTS C-G CORP. (US) 1979-02-13 US disclosed
US-4115575-A CARDIOVASCULAR DISORDERS CIBA-GEIGY CORPORATION (US) 1978-09-19 US disclosed
US-4027027-A BETA-RECEPTOR-BLOCKERS, HYPOTENSIVES AND VALODILATORS; FOR TREATING ARRYTHMIAS AND ANGINA PECTORIS CIBA-GEIGY CORPORATION (US) 1977-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10808246-B2 Oligonucleotide-ligand conjugates and process for their preparation RTCB, IGF2BP2, SNRPE DNM1 1874/4885BCHE 4801/4885ALDH1A1 1611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.