Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYBB | P04839 | 1/20 | 0.33 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.33 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30793120 | 0.88 | GPR119 (0.37) | MAPTMEN1KMT2ASCN9ANR1H2 | |
| SCHEMBL25337124 | 0.87 | KMT2A (0.36) | MAPTMEN1KMT2ANR1H2HPGD | |
| SCHEMBL30793341 | 0.87 | MEN1 (0.38) | MAPTMEN1KMT2ANR1H2GPR119 | |
| SCHEMBL30793390 | 0.85 | NR1H2 (0.36) | MAPTMEN1KMT2ASCN9ANR1H2 | |
| SCHEMBL24535292 | 0.84 | GPR119 (0.39) | MAPTMEN1KMT2ANR1H2GPR119 | |
| SCHEMBL31323684 | 0.82 | ADORA1 (0.42) | MAPTMEN1KMT2AGPR119HPGD | |
| SCHEMBL30793319 | 0.79 | MEN1 (0.37) | MAPTMEN1KMT2ASCN9ANR1H2 | |
| SCHEMBL30793811 | 0.77 | MEN1 (0.37) | MAPTMEN1KMT2ANR1H2HPGD | |
| SCHEMBL30793753 | 0.77 | MEN1 (0.37) | MAPTMEN1KMT2ANR1H2HPGD | |
| SCHEMBL25338426 | 0.77 | NR1H2 (0.43) | MAPTMEN1KMT2ANR1H2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4540254-A1 | TETRAHYDROPYRIDOPYRIMIDINE PAN-KRAS INHIBITORS | Mirati Therapeutics, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023244604-A1 | TETRAHYDROPYRIDOPYRIMIDINE PAN-KRAS INHIBITORS | Mirati Therapeutics, Inc. (US) | 2023-12-21 | — | — | WO | disclosed |