Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 11/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 11/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599401 | 1.00 | GRM5 (0.46) | GRM5HCRTR1HCRTR2HSD11B1IDO1 | |
| SCHEMBL599430 | 0.88 | HCRTR1 (0.49) | GRM5HCRTR1HCRTR2IDO1 | |
| SCHEMBL601360 | 0.88 | HCRTR1 (0.49) | GRM5HCRTR1HCRTR2IDO1 | |
| SCHEMBL7879633 | 0.86 | HCRTR2 (0.43) | GRM5HCRTR1HCRTR2HSD11B1NPC1 | |
| SCHEMBL7878360 | 0.83 | HCRTR2 (0.42) | GRM5HCRTR1HCRTR2HSD11B1NPC1 | |
| SCHEMBL601120 | 0.82 | HCRTR1 (0.45) | HCRTR1HCRTR2IDO1 | |
| SCHEMBL30795715 | 0.82 | HCRTR1 (0.45) | HCRTR1HCRTR2IDO1 | |
| SCHEMBL599266 | 0.82 | IDO1 (0.50) | GRM5HCRTR1HCRTR2HSD11B1IDO1 | |
| SCHEMBL599268 | 0.82 | IDO1 (0.50) | GRM5HCRTR1HCRTR2HSD11B1IDO1 | |
| SCHEMBL599267 | 0.82 | IDO1 (0.50) | GRM5HCRTR1HCRTR2HSD11B1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |