Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F12 | P00748 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3921053 | 1.00 | GRM5 (0.51) | GRM5ABCB11HDAC6METAP1HTT | |
| SCHEMBL3923785 | 0.82 | GRM5 (0.64) | GRM5METAP1HTTRAB9AL3MBTL1 | |
| SCHEMBL30795324 | 0.82 | GRM5 (0.64) | GRM5METAP1HTTRAB9AL3MBTL1 | |
| SCHEMBL5669525 | 0.80 | GRM5 (0.55) | GRM5METAP1HTTRAB9AL3MBTL1 | |
| SCHEMBL19120907 | 0.80 | FLT3 (0.61) | GRM5METAP1HTTRAB9AL3MBTL1 | |
| SCHEMBL4316115 | 0.80 | ABCB11 (0.55) | ABCB11HDAC6HTTRAB9AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL5672104 | 0.79 | GRM5 (0.53) | GRM5METAP1HTTRAB9AL3MBTL1 | |
| SCHEMBL2192371 | 0.78 | FLT3 (0.72) | GRM5METAP1FLT3 | |
| SCHEMBL12857463 | 0.77 | ABCB11 (0.58) | ABCB11HDAC6HTTRAB9AL3MBTL1 | |
| SCHEMBL3922838 | 0.75 | KDM4E (0.51) | GRM5METAP1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |