Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 6/20 | 0.43 |
| ▸ | ALDH1A2 | O94788 | 3/20 | 0.43 |
| ▸ | GRM5 | P41594 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL101349 | 1.00 | ALDH1A3 (0.43) | ALDH1A3ALDH1A2GRM5ALDH1A1NPC1 | |
| SCHEMBL101358 | 0.85 | GRM5 (0.41) | GRM5MAPTTSHRNPSR1 | |
| SCHEMBL103615 | 0.84 | GRM5 (0.40) | GRM5MAPTPDE10ANPSR1 | |
| SCHEMBL30794317 | 0.84 | GRM5 (0.40) | GRM5MAPTPDE10ANPSR1 | |
| SCHEMBL104087 | 0.82 | GRM5 (0.42) | GRM5ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL132127 | 0.75 | GRM5 (0.47) | GRM5 | |
| SCHEMBL5258543 | 0.74 | GRM5 (0.66) | GRM5SMN1; SMN2 | |
| SCHEMBL102850 | 0.73 | GRM5 (0.70) | GRM5ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL103337 | 0.69 | GRM5 (0.42) | GRM5 | |
| SCHEMBL100452 | 0.68 | GRM5 (0.57) | GRM5ALDH1A1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |