Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 5/20 | 0.56 |
| ▸ | MAOB | P27338 | 5/20 | 0.56 |
| ▸ | ALPL | P05186 | 6/20 | 0.55 |
| ▸ | ALPI | P09923 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29226062 | 0.88 | HSD17B3 (0.69) | HSD17B3MAOAMAOBALPLALPI | |
| SCHEMBL19635944 | 0.84 | HSD17B3 (0.60) | HSD17B3MAOAMAOBALPLALPI | |
| SCHEMBL30876199 | 0.84 | HSD17B3 (0.60) | HSD17B3MAOAMAOBALPLALPI | |
| SCHEMBL3076160 | 0.82 | HSD17B3 (0.57) | HSD17B3MAOAMAOBALPLALPI | |
| SCHEMBL3078189 | 0.82 | HSD17B3 (0.57) | HSD17B3MAOAMAOBALPLALPI | |
| SCHEMBL3086227 | 0.81 | HSD17B3 (0.60) | HSD17B3MAOAMAOBALPLALPI | |
| SCHEMBL3086146 | 0.79 | HSD17B3 (0.57) | HSD17B3MAOAMAOBALPLALPI | |
| SCHEMBL11067092 | 0.78 | KDM4E (0.66) | HSD17B3MAOAMAOBALPLALPI | |
| SCHEMBL3073187 | 0.76 | GPR35 (0.50) | HSD17B3MAOAMAOBALPLALPI | |
| SCHEMBL29206959 | 0.75 | HSD17B3 (0.73) | HSD17B3MAOAMAOBALPLALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005599-A | 7-Aminocoumarin derivative and synthetic method and application thereof | 陕西科技大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-112409345-A | Preparation method of novel dihydropyronyl coumarin compound | 大连理工大学 | 2021-02-26 | — | — | CN | disclosed |
| EP-2825261-A1 | POLYPEPTIDES AND THEIR USE | Novabiotics Limited (GB) | 2015-01-21 | — | — | EP | disclosed |
| US-20140155321-A1 | Polypeptides and Their Use | NOVABIOTICS LIMITED (GB) | 2014-06-05 | — | — | US | disclosed |
| WO-2013136040-A1 | POLYPEPTIDES AND THEIR USE | NOVABIOTICS LIMITED (GB) | 2013-09-19 | — | — | WO | disclosed |
| US-20100267653-A1 | USE OF COUMARIN DERIVATIVES IN ANTIFUNGAL THERAPY | NOVABIOTICS LIMITED (GB) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267653-A1 | USE OF COUMARIN DERIVATIVES IN ANTIFUNGAL THERAPY | DPM1, XPO5, NISCH | HSD17B3 239/4885MAOA 3643/4885MAOB 3597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.